Science corner
Explore the science behind PEMF and laser therapy—how they work, their benefits, and supporting research. Use the navigation to access PEMF and laser data, including mechanisms of action, history, and case studies.
What is Laser Therapy or Photobiomodulation?
Laser therapy, also known as low-level laser therapy (LLLT), involves using low-intensity laser light to stimulate healing and reduce pain and inflammation. It is a non-invasive treatment that applies specific wavelengths of light (600-1000nm) to penetrate tissues and promote cellular function and repair.
How Does Laser Therapy Work?
Laser therapy works through a process called photobiomodulation, where light photons are absorbed by cellular photoreceptors, particularly the chromophores in the mitochondria.
Mechanisms of Action:
Laser therapy impacts cellular activity in several ways:
ATP Production and Enhanced Cellular Metabolism
Light photons are absorbed by photoreceptors, mainly cytochrome c oxidase in mitochondria, boosting ATP production and cellular metabolism for repair and regeneration.
Nitric Oxide
Laser therapy increases nitric oxide production, which improves blood flow, oxygenation, and nutrient delivery to tissues.
ROS (Reactive oxygen species
The temporary rise in ROS levels from laser therapy signals various cellular processes, promoting repair, regeneration, and anti-inflammatory responses.
Cytokine Activity
The therapy modulates the inflammatory response by decreasing pro-inflammatory cytokines and increasing anti-inflammatory cytokines.
Collagen Production
Laser therapy stimulates fibroblast and collagen production, promoting tissue repair and regeneration.
Health and Body Benefits:
Overall Well-being
Regular laser therapy sessions can improve the general well-being of animals, supporting their health and vitality.
Pain Relief
By reducing inflammation and modulating pain pathways, laser therapy provides significant pain relief for animals with acute or chronic conditions.
Improved Mobility
By alleviating pain and reducing inflammation, laser therapy enhances mobility in animals with musculoskeletal issues.
Accelerated Healing
The enhanced cellular repair and improved blood flow speed up the healing process for injuries, wounds, and surgical sites.
Reduced Inflammation
Laser therapy helps manage conditions like arthritis and other inflammatory disorders, reducing discomfort and improving mobility.
FDA Approvals and CLEARANCES
The use of lasers in medicine dates back to the 1960 and since thenlaser therapy has been extensively studied and used for various medical applications, including pain management, wound healing, and musculoskeletal conditions.
— LLLT for Chronic Neck and Shoulder Pain – FDA Approved 2000
— LLLT for Post-Surgery Pain – FDA Approved 2004
— LLLT for Joint Pain, Arthritis and Muscle Pain- FDA approved 2016
Research Library
The list below features key studies on Laser therapy. Use it as a resource to explore scientific findings and deepen your understanding of these technologies.
DIG DEEPER
Explore blog posts with in-depth insights and technical information on Laser therapy.
Laser SUCCESS STORIES
See how top athletes, experts, and pet owners have experienced transformative results with Respond therapy systems, integrating them into their training, recovery, and wellness routines.
See more success stories
Swelling was completely gone in just 3 days, and within a week, the gelding was walking soundly. After 3 weeks, a check-up confirmed he was ready to begin conditioning."
Started laser treatment… A week later, the pocket of separation had decreased, and both the vet and farrier were surprised by the rapid progress."
Within 1 week, the wound had decreased in inflammation and size. Within 2 weeks, the wound was almost closed. By 5 weeks, the wound was fully closed and fur was growing back."
There is no question in my mind that the 2400VS class 3b cold laser system was a tremendous, and effective tool in his recovery."
I used the 2400XL laser today to treat this 3-month-old lamb… after the first treatment, she was able to position her neck in a neutral position and fell comfortably asleep."
